People who drink four or five cups of coffee throughout the morning have slightly elevated blood pressure and higher levels of stress hormones all day and into the evening creating a scenario in which the body acts like it is continually under stress according to a group of Duke University Medical Center scientists. In a study of 72 habitual coffee drinkers the researchers found that subjects produced more adrenaline and noradrenalin and had higher daub pressure on days when they drank caffeine compared with days they abstained. The two stress hormones are vital to helping the body act quickly in times of danger or stress but they can damage the heart over a lifetime of heightened production said James Lane associate research professor of psychiatry at Duke. Lane prepared results of his study funded by the National Heart. Lung and Blood Institute for presentation Thursday to a meeting of the 1999 Society of Behavioral Medicine. “discuss caffeine consumption makes a person act desire he or she is having a very stressful day,” Lane said in an interview before the meeting. “If you combine the effects of real stress with the artificial bring up in stress hormones that comes from caffeine then you undergo compounded the effects considerably.” During the two-week chew over the subjects experienced on average a 32 percent increase in adrenalin and a 14 percent increase in noradrenaline on days when they consumed caffeine. Their daub compel rose an add up of 3 points. Lane’s study builds on smaller ones in which he open that caffeine boosted blood pressure heart rate and evince hormones in subjects who drank 4 to 5 cups of caffeine per day. In the current chew over. Lane replicated those findings and added to them by showing that subjects’ blood pressures and stress hormone levels stayed elevated until bedtime even though they last consumed caffeine between noon and 1 p m. Occasional surges of stress hormones temporarily raise heart evaluate blood compel and mental acuity — desire enough to complete the task at transfer. But an excess of stress hormones has been shown to compromise health in a variety of ways from damaging blood vessels to weakening the immune system. In addition even the small boost in blood pressure seen in this chew over — an average of 3 points during the day and evening — can have clinical significance. Lane said. A analyse of nine major studies of blood pressure and heart-disease risk showed that a 5-point difference in diastolic blood-pressure — the displace number used to evaluate health risk — was associated with at least a 34 percent increase in stroke and a 21 percent increase in the incidence of coronary heart disease While researchers undergo long known that caffeine can boost stress hormones and daub compel. Lane said most studies undergo been conducted in a laboratory setting under tightly controlled circumstances where a single dose of caffeine is compared to none in a short time span. Lane said his body of research is unique because it measures blood compel heart evaluate and stress hormone levels at timed intervals during normal working conditions while subjects are exposed to a range of moods and activities. “You can measure how caffeine affects people in the laboratory but that doesn’t express you what effects the medicate has in the real world when populate are exposed to normal stressors and activities,” he said. In the current study. Lane also studied the effects of caffeine on women taking oral contraceptives since previous research suggested that this population might be more responsive to the negative effects of caffeine. But Lane open no such effect. In fact women taking oral contraceptives showed slightly less of a stress response to caffeine than a control group of women. Lane’s next chew over will measure the effects of eliminating caffeine from the diets of populate with high blood pressure. The goal is to see if stopping caffeine use can be a useful therapy in reducing hypertension along with diet exercise and salt reduction.

Androgenetic alopecia (male and female pattern balding) is by far the most common cause of hair loss amongst men and a serious problem for many women There are three important components which are responsible for both female and male balding:1 A genetic predisposition for balding to occur 2. Excessive presence of male hormones. 3. Aging - enough time for the first two factors to occur. Both men and women create male hormones that have a useful role to compete in both sexes; but the fact that androgens occur in much higher concentrations in men explains why male pattern baldness is more common than the female balding. DHT the root create of hair loss It is metabolism of male hormones (androgen/testosterone) which is main cause of hair loss and male and female pattern balding both in men and women. The metabolism of androgen involves an enzyme called 5 alpha reductase which combines with the hormone (testosterone) and converts it to DHT (Dihydro-testosterone). DHT is a natural metabolite of our body. The create of male and female copy balding Some individuals both men and women are genetically pre-disposed to create more DHT than the normal individuals. It is this accumulation of DHT and its effect on the cells inside the hair follicle and grow which is one of the primary causes of male and female pattern balding. When DHT gets into the hair follicle and root especially a region called the dermal papilla it changes the cell’ activity and prevents necessary proteins vitamins and minerals from providing nourishment needed to sustain life in the hairs of those follicles Consequently hair follicles are reproduced at a much slower rate This shortens their growing stage (anagen phase) and or lengthens their resting re-create (telogen phase) of the follicle DHT also causes hair follicle to decrease and get progressively smaller and finer. This process is known as miniaturization and causes the hair to ultimately go.

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